James Hewett University Professor of Chemistry
Chemistry
704 Hamilton HallLincoln, NE 68588
(402) 472-2744
dhage1@unl.edu
Education
- Postdoctoral, Mayo Clinic
- Ph.D., Iowa State University
- B.S., University of Wisconsin
Research Interests
- Analytical and bioanalytical chemistry
- Analytical separation methods
- High-performance liquid chromatography
- Capillary electrophoresis
- Affinity-based separations
- Affinity mass spectrometry
- Monolithic supports and hybrid separation media
- Affinity microcolumns and miniaturized separation systems
- Separation-based studies of biological interactions
- Analytical methods for personalized medicine
- Chromatographic immunoassays
- Immobilization methods for biochemicals
Selected Publications
- Sobansky, M.R.; Hage, D.S. "Identification and analysis of stereoselective drug interactions with low density lipoprotein by high-performance affinity chromatography", Anal. Biochem. Chem. 2012;403;563-71.
- Matsuda, R.; Anguizola, J.; Joseph, K.S.; Hage, D.S. "High-performance affinity chromatography and the analysis of drug interactions with modified proteins: binding of gliclazide with glycated human serum albumin", Anal. Bioanal. Chem. 2011;401;2811-19.
- Barnaby, O.S.; Cerny, R.L.; Clarke, W.; Hage, D.S. "Quantitative analysis of glycation patterns in human serum albumin Using 16O/18O-labeling and MALDI-TOF MS", Clin. Chim. Acta 2011;412;1606-15.
- Tong, Z.; Hage, D.S. "Characterization of interaction kinetics between chiral solutes and human serum albumin by using high-performance affinity chromatography and peak profiling", J. Chromatogr. A 2011;1218;6892-7.
- Hage, D.S.; Anguizola, J.A.; Jackson, A.J.; Matsuda, R.; Papastavros, E.; Pfaunmiller, E.; Tong, Z.; Vargas-Badilla, J.; Yoo, M.J.; Zheng, X. "Chromatographic analysis of drug interactions in the serum proteome", Anal. Methods 2011;3;1449-60.
- Yoo, M.J.; Hage, D.S. "High-throughput analysis of drug dissociation from serum proteins using affinity silica monoliths", J. Sep. Sci. 2011;34;2255-63.