Srivatsan Kidambi

Srivatsan Kidambi.

Associate Professor and Graduate Chair
Chemical and Biomolecular Engineering

207F Othmer Hall
Lincoln, NE 68588
(402) 472-4443
skidambi2@unl.edu
Faculty Profile

FOCμS LAB

@Prof_Kidambi on Twitter

Education
  • Postdoctoral Research Fellow, Harvard Medical School and Massachusetts General Hospital, 2009
  • Ph.D., Chemical Engineering and Materials Science, Michigan State University, 2007
  • M.S., Chemistry, Michigan State University, 2002
  • B.S., Chemistry, University of Madras, India, 1999

Research Interests
  • Liver Tissue Engineering
  • Cancer Tissue Engineering
  • Biomimetic Models of Aging Brain
  • Nano-scale Drug Delivery System for Gene Therapy

Honors and Awards
  • 2013 Young Investigator Award, International Symposium on the Cells of the Hepatic Sinusoid
  • 2009 DoD Prostate Cancer Postdoctoral Fellowship
  • 2009 Elected to Sigma Xi, Full Member, Harvard Chapter
  • 2007 American Chemical Society ICI Student Award Finalist in Applied Polymer Science
  • 2006 ACS Excellence Award in Polymer Science
  • 2000 Walter and Margaret Yates Memorial Scholarship

Inventions/Patents
  • “Cell Adhesion on Surfaces of Varying Topographies” US 20080241926
  • “Salt and pH tunable Polyelectrolyte Multilayers for uses as bioengineering scaffolds” US 20070224175
  • “Development of Polyelectrolyte Multilayer Coatings for Primary Hepatocyte Cell Culture System” (MSU Invention Number 06-026).
  • “Aptamer Arrays on Polyelectrolyte Multilayer Films” (MSU Invention Number 05-117F)

Selected Publications
  • “Astrogliosis in a Dish: Substrate Stiffness Induces Astrogliosis in Primary Rat Astrocytes” Christina Wilson, Stephen Hayward, Srivatsan Kidambi*, RSC Advances, 2016 (Impact Factor = 3.84)
  • "Hyaluronic acid-conjugated liposome nanoparticles for targeted delivery to CD44 overexpressing glioblastoma cells”, Stephen Hayward, Christina Wilson, Srivatsan Kidambi*, OncoTarget, 2016 (Impact Factor = 6.4)
  • Targeted Delivery of MicroRNA-125a-5p by Engineered Lipid Nanoparticles for the Treatment of HER2 positive Metastatic Breast Cancer”, Stephen Hayward, David Francis, Parviz Kholmatov, Srivatsan Kidambi*, Journal of Biomedical Nanotechnology, 2016 doi: 10.1166/jbn.2016.2194 (Impact Factor = 5.4)
  • “Ionic Driven Embedment of Hyaluronic Acid Coated Liposomes in Polyelectrolyte Multilayer Films for Local Therapeutic Delivery”, Stephen Hayward, David Francis, Matthew Sis, Srivatsan Kidambi*, Nature Scientific Reports, 2015, doi: 10.1038/srep14683 (Impact Factor = 5.6)
  • “Substrate elasticity regulates primary hepatocytes functions”, Vaishaali Natarajan, Eric Berglund, Dorothy Chen, Srivatsan Kidambi*, RSC Advances, 2015, doi: 10.1039/C5RA15208A (Impact Factor = 3.84)
  • “In vitro Co-cultures of Breast Cancer Cells and Stromal Cells to Emulate Tumor Progression and miRNA Profiles of Clinical Conditions”, Amita Daverey, Karleen Brown, Srivatsan Kidambi*, Langmuir, 2015 doi: 10.1021/acs.langmuir.5b02227 (Impact Factor = 4.0)
  • “Physical Intimacy of Breast Cancer Cells with Mesenchymal Stem Cells Elicits Trastuzumab Resistance through Src Activation” Amita Daverey, Allison Drain, Srivatsan Kidambi*, Nature Scientific Reports, 2015 doi: 10.1038/srep13744 (Impact Factor = 5.6)
  • “Mitochondrial Dysfunction and Loss of Glutamate Uptake in Primary Astrocytes Exposed to Titanium Dioxide Nanoparticles”, Christina Wilson, Vaishaali Natarajan, Stephen Hayward, Oleh Khalimonchuk, Srivatsan Kidambi*, Nanoscale, 2015 doi: 10.1039/C5NR03646A (Impact Factor = 7.4)
  • “Mitochondrial Dysregulation and Loss of Hepatic Functions due to Chronic Exposure to Titanium dioxide Nanoparticles to Primary Hepatocytes”, Vaishaali Natarajan, Christina Wilson, Stephen Hayward, Srivatsan Kidambi*, PLOS One, 2015 doi: 10.1371/journal.pone.0134541 (Impact Factor = 3.53)
  • “Dye-doped silica encapsulated magnetic nano-assemblies for dual optical/MRI imaging and hyperthermia", Sunil Kumar, Dhirendra Bahadur, Amita Daverey, Vahid Khalilzad-Sharghi, Niroj Sahu, Niroj; Srivatsan Kidambi, Shadi Othman, RSC Advances, 5, 53180-53188, 2015 doi: 10.1039/C5RA07632C (Impact Factor = 3.84)
  • “FMR1 Deficiency Alters Self-Renewal, Proliferation, and Pluripotency of Mouse Embryonic Cells”, Shyam Sundhar Bale; Nima Saeidi; Srivatsan Kidambi; Martin Yarmush; Monica Casali, NanoLife, 5(2), 15500, 2015 doi: 10.1142/S1793984415500038
  • “Engineering of highly controlled in vitro co-culture model to study the mesenchymal stem cells mediated signaling in breast cancer cells”, Amita Daverey, Allison Drain, Karleen Drain, Srivatsan Kidambi*, Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; Cancer Res 2014; 74 (19 Suppl). doi:10.1158/1538-7445.AM2014-3303
  • “Topography Mediated Regulation of HER-2 Expression in Breast Cancer Cells” Amita Daverey, Austin Mytty, Srivatsan Kidambi *, NanoLife, 2(3), 12410, 2012 doi: 10.1142/S1793984412410097
  • “Propofol induces MAPK/ERK cascade dependant expression of c-Fos and Egr-1 in rat hippocampal slices” Srivatsan Kidambi*, Joel Yarmush, Yevgeny Berdichevsky, Sangeetha Kamath, Wayne Fong, Joseph SchianodiCola, BMC Research Notes, 17(3), 201-206, 2010