Faculty - Krasnoslobodtsev

Alexey V. Krasnoslobodtsev

Alexey V. Krasnoslobodtsev

Alexey V. Krasnoslobodtsev
Associate Professor

Department of Physics
University of Nebraska Omaha
119 Durham Science Center
Omaha, NE 68182
Office: 402-554-3723

Education

  • B.S., Novosibirsk State University, Novosibirsk, Russia
  • M.S., New Mexico State University, Las Cruces, NM
  • Ph.D., New Mexico State University, Las Cruces, NM

About

Dr. Krasnoslobodtsev joined the Department of Physics at UNO in August of 2014 where he is currently an Associate Professor.
After completion of his PhD at New Mexico State University he came to Omaha to continue his passion of doing research in single-molecule biophysics. Dr. Krasnoslobodtsev joined a research group of Dr. Lyubchenko at the Department of Pharmaceutical Sciences University of Nebraska Medical Center learning, improving and utilizing single-molecule biophysical techniques to primarily answer fundamental questions related to malfunctioning of DNA-protein and protein-protein systems. Dr. Krasnoslobodtsev continues to use single-molecule techniques at UNO. His laboratory currently has Tethered Particle Motion setup, Single-molecule Fluorescence, Total Internal Reflection Fluorescence, and Raman spectrometer used to study effects of Enhanced Raman Scattering and utilize these effects for biomedical applications.
Dr. Krasnoslobodtsev is also an Adjunct Professor at the College of Pharmacy and Director of Nanoimaging Core Facility, University of Nebraska Medical Center.


Research Interests

Dr. Krasnoslobodtsev’s research interests lie at the interface of nanotechnology, biology and physics. His research program uses principles of these disciplines to answer fundamental questions of biology that can facilitate early diagnostics and effective therapeutic solutions. Specific examples of the research projects are: single molecule studies of molecular mechanisms of protein misfolding phenomenon and protein-protein interactions; combination of nanoimaging and nanomanipulation with spectroscopic techniques and development of hybrid biosensing nano-platforms with high sensitivity.


Recent Publications

  1. Liam E. Yourston; Alexander Y. Lushnikov; Oleg A. Shevchenko; Kirill A. Afonin; Alexey V Krasnoslobodtsev, “First Step Towards Larger DNA-Based Assemblies of Fluorescent Silver Nanoclusters: Template Design and Detailed Characterization of Optical Properties”, Nanomaterials. 2019, 9(4), 613.
  2. Sameer Sajja, Morgan Chandler, Dmitry Fedorov, Wojciech K. Kasprzak, Alexander Lushnikov, Mathias Viard, Ankit Shah, Dylan Dang, Jared Dahl, Beamlak Worku, Marina A. Dobrovolskaia, Alexey Krasnoslobodtsev, Bruce A. Shapiro, Kirill A. Afonin, “Dynamic behavior of RNA nanoparticles analyzed by AFM on a mica/air interface”, Langmuir, 2018, 34, 49, 15099-15108.
  3. Joseph Smolsky and Alexey Krasnoslobodtsev, “Nanoscopic imaging of oxidized graphene monolayer using Tip-Enhanced Raman Scattering”, NanoResearch. 2018, 11(12), 6346–6359.
  4. J. Smolsky, S. Kaur, Ch. Hayashi, S. Batra, and A. Krasnoslobodtsev, “Surface-Enhanced Raman Scattering-Based Immunoassay Technologies for Detection of Disease Biomarkers”, Biosensors, 2017, 7,
  5. Krasnoslobodtsev A, Deckert-Gaudig T , Zhang Y, Deckert V, Lyubchenko Y. “Polymorphism of amyloid fibrils formed by a peptide from the yeast prion protein Sup35: AFM and Tip-Enhanced Raman Scattering”, Ultramicroscopy, 2016, 165: 26-33.